Hello. Have you disabled secure boot in BIOS/UEFi Settings (F2 during startup… or Delete if F2 won't work). Although I have disabled it, my Akoya 2218S hasn't started successfully any UEFI compatible 64bit linux distro from pendrive. (32 bit neither.) Although that, now I can use every distro I want (even with persistence mode). I do it with Ventoy tools. Here is project site: https://www.ventoy.net/ (If you mind Ventoy, theres probably some way to boot pendrive with „internal shell”. Here is something common: https://ourcodeworld.com/articles/read/982/how-to-format-medion-akoya-s2218-laptop-with-windows-10-using-a-usb-and-the-efi-shell Try Ventoy and good luck! Probably, your next question here will be: How to make sound card work in Linux? 😉 I don't know so far 😕 I had much work with starting it in Windows 10 20H2 32-bit, pure installation. If anyone need to know – after 10 days i found out, W10 20H2 works perfectly with Windows 8 drivers.
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